| CAS No.: | 54-21-7 |
|---|---|
| Formula: | C7h5nao3 |
| EINECS: | 200-198-0 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Pharmaceutical Grade |
| Customization: |
|---|
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Audited Supplier | Item | Index | Result |
| Appearance | White crystalline powder, soluble in water. It dissolves in dilute acid and alkaline solutions. | Conform |
| Identification | a) TLC results | Conform |
| b) Color reaction with sulfuric acid | Conform | |
| c) Color reaction with silver nitrate | Conform | |
| Ph | 4.5 to 7.0 | 6 |
| Specific optical rotation | -203°to -216°° | -206° |
| Specific absorbance at 353nm | 290 to 310 | 308 |
| Light-absorbing impurities | a) At 430nm not greater than 0.25 | 0.08 |
| b) At 490nm not greater than 0.20 | 0.01 | |
| Related substances | 4-epioxytetracycline≤ 0.5% | 0.20% |
| Tetracycline hydrochloride≤2.0% | 0.30% | |
| Peak on the tail of the main peak≤2.0% | 1.60% | |
| Heavy metals | Not more than 50ppm | <50ppm |
| Water | 6.0 % to 9.0% | 7.70% |
| Sulphated ash | Not more than 0.5% | 0.03% |
| Assay | 95.0% -100.5%(C22H24N2O9) based onanhydrous substance | 99.10% |
It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID),and induces apoptosis in cancer cells and also necrosis.It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultraviolet radiation and electrons.
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